Phospholipase A1 of human blood platelets (Short Communication) |
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| Authors: | J. B. Smith M. J. Silver G. R. Webster |
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| Affiliation: | Cardeza Foundation and Department of Pharmacology, Thomas Jefferson University, Philadelphia, Pa. 19107, U.S.A., and Department of Pharmacology, Royal College of Surgeons of England, London WC2A 3PN, U.K.;Department of Chemical Pathology, Guy''s Hospital Medical School, London SE1 9RT, U.K. |
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| Abstract: | Substantial phospholipase A(1) activity has been demonstrated in human blood platelets, and a rapid method for its measurement is described. The enzyme requires taurocholate for full activity and in these conditions the pH optimum is 4.8. The phospholipase activity is released from platelets by incubation with thrombin. |
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