Effect of brefeldin A and actinomycin D on culture growth and brefeldin A yield inCurvularia lunata |
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| Authors: | C T Sam |
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| Institution: | 1. Department of Pharmacy, University of Sydney, 2006, Sydney, New South Wales, Australia
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| Abstract: | Cultures incorporated with increasing quantities of brefeldin A in the form of crude extracts of fungal metabolites prior to inoculation demonstrated reduced growth rate and no significant increase in brefeldin A content. On the other hand, cultures incubated with increasing levels of actinomycin D on the 8th day of cultivation showed slight stimulation of brefeldin A formation with insignificant effect on growth. |
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