In vitro and clinical evaluation of specific dentifrices for complete denture hygiene |
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Authors: | Panzeri Heitor Lara Elza Helena Guimarães Paranhos Helena de Freitas Oliveira Lovato da Silva Claudia Helena de Souza Raphael Freitas de Souza Gugelmin Maria Cristina Monteiro Tirapelli Camila Cruz Patrícia Costa de Andrade Ingrid Machado |
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Institution: | 1. Department of Dental Materials and Prosthodontics, Ribeir?o Preto School of Dentistry, University of S?o Paulo, Ribeir?o Preto, Brazil;2. Department of Pharmaceutical Sciences, Ribeir?o Preto Faculty of Pharmaceutical Sciences, University of S?o Paulo, Ribeir?o Preto, Brazil;3. Department of Clinical, Toxicological and Bromatological Analyses, Ribeir?o Preto Faculty of Pharmaceutical Sciences, University of S?o Paulo, Ribeir?o Preto, Brazil |
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Abstract: | Objectives: To study the physical properties of two experimental dentifrices for complete denture hygiene, their effect on denture biofilm removal and antimicrobial properties by means of a clinical trial. Materials and methods: The experimental dentifrices comprised two compositions. One was based on the addition of 1% chloramine T (D1) and the other on the presence of 0.01% fluorosurfactant (D2). Measurements of density, pH, consistency, rheological features and abrasiveness were conducted. Sixty complete denture wearers were randomly assigned to three groups and were instructed to brush their dentures with a specific toothbrush: (1) Water (control); (2) D1; or (3) D2. Each method was used for 21 days. Denture biofilm was disclosed by a 1% neutral red solution and quantified by means of digital photos taken from the internal surface. Microbiological assessment was conducted to quantify Candida sp. and mutans streptococci. Data were evaluated by one‐way anova and Tukey HSD, or Kruskal–Wallis (α = 0.05). Results: Both dentifrices decreased biofilm coverage when compared with the control group. D1 was the most efficacious treatment to reduce mutans streptococci, whereas D2 showed an intermediate outcome (anova , p < 0.040). No treatment influenced Candida albicans or non‐albicans species (Kruskal–Wallis, p = 0.163 and 0.746, respectively). Conclusion: It can be concluded that brushing complete dentures with the experimental dentifrices tested could be effective for the removal of denture biofilm. |
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Keywords: | complete denture biofilm denture cleansers dentifrices |
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