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枝顶孢属真菌的抑菌活性及其代谢产物研究
引用本文:姚磊,徐良雄,薛璟花,魏孝义,吴萍. 枝顶孢属真菌的抑菌活性及其代谢产物研究[J]. 热带亚热带植物学报, 2012, 20(2): 192-196
作者姓名:姚磊  徐良雄  薛璟花  魏孝义  吴萍
作者单位:1. 中国科学院华南植物园,中国科学院植物资源保护与可持续利用重点实验室,广州510650;中国科学院研究生院,北京100049
2. 中国科学院华南植物园,中国科学院植物资源保护与可持续利用重点实验室,广州510650
基金项目:国家自然科学基金项目(20672114)资助
摘    要:用组织分离法从采集于广东鼎湖山的腐殖质中分离得到一株枝顶孢属真菌(Acremonium sp. SC0105),其固体发酵物的乙醇提取物对金黄色葡萄球菌(Staphylococcus aureus)有较强的抑制作用。经多种柱层析,从固体发酵物中分离得到5个化合物。通过光谱分析,分别鉴定为姜糖脂B (1)、姜糖脂C (2)、D-甘露醇(3)、酒渣碱(4)、枝顶孢素F(5)。其中酒渣碱是首次从枝顶孢属真菌中分离得到。

关 键 词:枝顶孢属  抑菌  姜糖脂  酒渣碱  枝顶孢素F
收稿时间:2011-04-27
修稿时间:2011-07-13

Antibacterial Activity and Metabolits of an Acremonium Fungus
YAO Lei,XU Liang-xiong,XUE Jing-hu,WEI Xiao-yi and WU Ping. Antibacterial Activity and Metabolits of an Acremonium Fungus[J]. Journal of Tropical and Subtropical Botany, 2012, 20(2): 192-196
Authors:YAO Lei  XU Liang-xiong  XUE Jing-hu  WEI Xiao-yi  WU Ping
Affiliation:1. Key Laboratory of Plant Resources Conservation and Sustainable Utilization, South China Botanical Garden, Chinese Academy of Sciences, China; 2. Graduate University of Chinese Academy of Sciences, China;Key Laboratory of Plant Resources Conservation and Sustainable Utilization, South China Botanical Garden, Chinese Academy of Sciences, China;Key Laboratory of Plant Resources Conservation and Sustainable Utilization, South China Botanical Garden, Chinese Academy of Sciences, China;Key Laboratory of Plant Resources Conservation and Sustainable Utilization, South China Botanical Garden, Chinese Academy of Sciences, China;Key Laboratory of Plant Resources Conservation and Sustainable Utilization, South China Botanical Garden, Chinese Academy of Sciences, China
Abstract:A fungal strain of Acremonium sp. SC0105 was obtained from tissue culture of humus collected at Dinghushan, Guangdong Province, China. The EtOH extract of this fungal strain showed antibacterial activity against Staphylococcus aureus. From the solid cultures of this fungus, five compounds were isolated by repeated column chromatography. On the basis of their spectral data, they were identified as gingerglycolipid B (1), gingerglycolipid C (2), D-Mannitol (3), flazine (4), and acremine F (5). Among them, flazine (4) was isolated from fungus of Acremonium genus for the first time.
Keywords:Aremonium sp.  Antibacterium  Gingerglycolipid  Flazine  Acremine F
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