BrEPS: a flexible and automatic protocol to compute enzyme-specific sequence profiles for functional annotation |
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Authors: | C Bannert A Welfle C aus dem Spring D Schomburg |
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Institution: | 1.Dept. of Bioinformatics and Biochemistry,Technische Universit?t Braunschweig,Braunschweig,Germany |
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Abstract: | Background Models for the simulation of metabolic networks require the accurate prediction of enzyme function. Based on a genomic sequence,
enzymatic functions of gene products are today mainly predicted by sequence database searching and operon analysis. Other
methods can support these techniques: We have developed an automatic method "BrEPS" that creates highly specific sequence
patterns for the functional annotation of enzymes. |
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