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Suppression of synthesis of serotonin: Effect on antinociception induced by microwave irradiation and analgesic remedies
Authors:E. Nesin
Affiliation:(1) Bogomolets Institute of Physiology, National Academy of Sciences of Ukraine, Kyiv, Ukraine
Abstract:We studied isolated and combined antinociceptive effects of analgesics (Analginum and Tramadol), as well as of microwave irradiation of an acupuncture point, in mice under conditions of suppression of synthesis of serotonin by an inhibitor of this synthesis, DL-p-chlorophenylalanine (p-CPA). Preliminary introduction of p-CPA weakened the antinociceptive effect of microwave irradiation and also moderated the combined effects of analgesics and microwave irradiation. Neirofiziologiya/Neurophysiology, Vol. 38, Nos. 5/6, pp. 498–499, September–December, 2006.
Keywords:analgesia  formalin test  analgesics  microwave irradiation  DL-p-chlorophenylalanine
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