Suppression of synthesis of serotonin: Effect on antinociception induced by microwave irradiation and analgesic remedies |
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Authors: | E. Nesin |
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Affiliation: | (1) Bogomolets Institute of Physiology, National Academy of Sciences of Ukraine, Kyiv, Ukraine |
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Abstract: | We studied isolated and combined antinociceptive effects of analgesics (Analginum and Tramadol), as well as of microwave irradiation of an acupuncture point, in mice under conditions of suppression of synthesis of serotonin by an inhibitor of this synthesis, DL-p-chlorophenylalanine (p-CPA). Preliminary introduction of p-CPA weakened the antinociceptive effect of microwave irradiation and also moderated the combined effects of analgesics and microwave irradiation. Neirofiziologiya/Neurophysiology, Vol. 38, Nos. 5/6, pp. 498–499, September–December, 2006. |
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Keywords: | analgesia formalin test analgesics microwave irradiation DL-p-chlorophenylalanine |
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