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Screening for natural inhibitors of human topoisomerases from medicinal plants with bio-affinity ultrafiltration and LC–MS |
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| Authors: | Fan Minxia Chen Guilin Sun Baoqing Wu Jianlin Li Na Sarker Satyajit D Nahar Lutfun Guo Mingquan |
| Institution: | 1.Key Laboratory of Plant Germplasm Enhancement and Specialty Agriculture, Wuhan Botanical Garden, Chinese Academy of Sciences, Wuhan, 430074, China ;2.University of Chinese Academy of Sciences, Beijing, 100049, China ;3.Sino-Africa Joint Research Center, Chinese Academy of Sciences, Wuhan, 430074, China ;4.State Key Laboratory of Respiratory Disease, National Clinical Center for Respiratory Diseases, Guangzhou Institute of Respiratory Diseases, The First Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong Province, China ;5.State Key Laboratory for Quality Research of Chinese Medicines, Macau University of Science and Technology, Taipa, Macao ;6.Medicinal Chemistry and Natural Products Research Group, School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Liverpool, L3 3AF, UK ; |
| Abstract: | Phytochemistry Reviews - The continuing rise in cancer morbidity and mortality all over the world makes cancer the No. 2 cause of death in humans, posing a major public health challenge. Currently,... |
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