QTLNetwork: mapping and visualizing genetic architecture of complex traits in experimental populations |
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Authors: | Yang Jian Hu Chengcheng Hu Han Yu Rongdong Xia Zhen Ye Xiuzi Zhu Jun |
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Affiliation: | Institute of Bioinformatics, Zhejiang University, Hangzhou, China, 310029. |
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Abstract: | SUMMARY: QTLNetwork is a software package for mapping and visualizing the genetic architecture underlying complex traits for experimental populations derived from a cross between two inbred lines. It can simultaneously map quantitative trait loci (QTL) with individual effects, epistasis and QTL-environment interaction. Currently, it is able to handle data from F(2), backcross, recombinant inbred lines and double-haploid populations, as well as populations from specific mating designs (immortalized F(2) and BC(n)F(n) populations). The Windows version of QTLNetwork was developed with a graphical user interface. Alternatively, the command-line versions have the facility to be run in other prevalent operating systems, such as Linux, Unix and MacOS. AVAILABILITY: http://ibi.zju.edu.cn/software/qtlnetwork. |
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