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Brainstem mechanisms underlying feeding behaviors
Authors:James P Lund  Arlette Kolta  Karl-Gunnar Westberg  George Scot
Institution:aFaculty of Dentistry and Department of Physiology, McGill University, 3640 University Street, Montréal, Québec, H3A 2B2 Canada;bCentre de recherche en sciences neurologiques, Université de Montréal, Montréal, Québec, H3C 3J7 Canada;cDépartment de Stomatologie, Université de Montréal, Montréal, Québec H3C 3J7, Canada;dDepartment of Physiology, Umeå University, S-901 87, Umeå, Sweden
Abstract:The essential elements controlling trigeminal motoneurons during feeding lie between the trigeminal and facial motor nuclei. These include populations of neurons in the medial reticular formation and pre-motoneurons in the lateral brainstem that reorganize to generate various patterns. Orofacial sensory feedback, antidromic firing in spindle afferents and intrinsic properties of motoneurons also contribute to the final masticatory motor output.
Keywords:Abbreviations: 5-HT 5-hydroxytryptamine (serotonin)  AMPA α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid  CPG central pattern generator  EAA excitatory amino acid  EMG electromyographic  EPSP excitatory postsynaptic potential  GABA γ-aminobutyric acid  IPSP inhibitory postsynaptic potential  JC jaw-closing  JO jaw-opening  d-aspartate" target="_blank">NMDAN-methyl-d-aspartate  npc nucleus pontis caudalis  nVII facial nucleus  nVmes mesencephalic trigeminal nucleus  nVmot trigeminal motor nucleus  nVsnpr trigeminal main sensory nucleus  RF reticular formation  RPc nucleus reticularis parvocellularis
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