SIC: A tool to detect short inverted segments in a biological sequence |
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Authors: | Robelin David Richard Hugues Prum Bernard |
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Affiliation: | Laboratoire Statistique et Génome, Tour Evry 2, 91000 Evry, France. robelin@genopole.cnrs.fr |
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Abstract: | The web software SIC provides a tool to search for short inverted segments (length 3-5000 bp) in a DNA sequence. The sequence is assumed to follow a Markov model. A statistic which is sensitive to inversion is presented. Searching inverted segments is done by a scanning approach after the user specifies the size of the scanning window and the order of the Markov chain. A list of the highest score segments is given with an assessment of the randomness of the result. SIC can be accessed via the URL: http://stat.genopole.cnrs.fr/SIC/. |
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