Expression and functional analysis of endoglin in isolated liver cells and its involvement in fibrogenic Smad signalling |
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| Authors: | Meurer Steffen K Tihaa Lidia Borkham-Kamphorst Erawan Weiskirchen Ralf |
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| Affiliation: | Institute of Clinical Chemistry and Pathobiochemistry, RWTH-University Hospital, D-52074 Aachen, Germany |
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| Abstract: | |
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| Keywords: | α-SMA, α-smooth muscle actin CTGF, connective tissue growth factor Eng, endoglin ER, endoplasmatic reticulum GAPDH, glyceraldehyde-3-phosphate dehydrogenase Hif-1α, hypoxia inducible factor 1α HSC, hepatic stellate cell(s) IP, immunoprecipitation KC, Kupffer cell(s) KLF6, Krü ppel-like factor 6 L-endoglin, full length endoglin (long variant) LSEC, liver sinusoidal endothelial cell(s) MFB, myofibroblast(s) NF-κB, nuclear factor-κB PC, parenchymal cells (hepatocytes) PDZ-domain, underline" >Post synaptic density- underline" >Discs large- underline" >Zonula occludentes homologous domain pMF, portal myofibroblast(s) S-endoglin, splice variant of endoglin (short variant) S&prime -endoglin, variant form of S-endoglin in rats sol, soluble TβR, TGF-β receptor |
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