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Expression and functional analysis of endoglin in isolated liver cells and its involvement in fibrogenic Smad signalling
Authors:Meurer Steffen K  Tihaa Lidia  Borkham-Kamphorst Erawan  Weiskirchen Ralf
Institution:
  • Institute of Clinical Chemistry and Pathobiochemistry, RWTH-University Hospital, D-52074 Aachen, Germany
  • Abstract:
    Keywords:α-SMA  α-smooth muscle actin  CTGF  connective tissue growth factor  Eng  endoglin  ER  endoplasmatic reticulum  GAPDH  glyceraldehyde-3-phosphate dehydrogenase  Hif-1α  hypoxia inducible factor 1α  HSC  hepatic stellate cell(s)  IP  immunoprecipitation  KC  Kupffer cell(s)  KLF6  Krü  ppel-like factor 6  L-endoglin  full length endoglin (long variant)  LSEC  liver sinusoidal endothelial cell(s)  MFB  myofibroblast(s)  NF-κB  nuclear factor-κB  PC  parenchymal cells (hepatocytes)  PDZ-domain  Post synaptic density-Discs large-Zonula occludentes homologous domain" target="_blank">Post synaptic density-Discs large-Zonula occludentes homologous domain  pMF  portal myofibroblast(s)  S-endoglin  splice variant of endoglin (short variant)  S&prime  -endoglin  variant form of S-endoglin in rats  sol  soluble  TβR  TGF-β receptor
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