A sexual rejection peptide: potential use for controlling mouse overpopulation |
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| Authors: | Takuya Osakada Takumi Itakura Ryo Kenmochi |
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| Institution: | 1. Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan;2. ERATO Touhara Chemosensory Signal Project, JST, The University of Tokyo, Tokyo, Japan |
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| Abstract: | Exocrine gland-secreting peptide 22 (ESP22) is a 10-kDa protein secreted in tears of juvenile mice. ESP22 inhibits sexual behaviors in adults, leading to a reduction in reproduction rate. We herein identified the 24 amino acid sequence within ESP22 that was essential for exhibiting sexual rejection activity. This synthesizable peptide can be useful for controlling mouse overpopulation. |
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| Keywords: | Peptide pheromone sexual behavior rejection vomeronasal mouse |
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