| Abstract: | Injection of intact bone marrow cells to mice at the peak of the secondary immune response results in a 2.4-fold increase of the number of antibody-forming cells in the regional lymph node. Preliminary injection of bone marrow cells to donors of the immune lymph node cells decreases the stimulation effect of antibody formation when the lymph node cells are subsequently cultivated with the intact bone marrow cells. The data obtained demonstrate the cell interaction at the level of mature antibody producers in vivo. |
