Psiscan: a computational approach to identify H/ACA-like and AGA-like non-coding RNA in trypanosomatid genomes |
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| Authors: | Inna Myslyuk Tirza Doniger Yair Horesh Avraham Hury Ran Hoffer Yaara Ziporen Shulamit Michaeli Ron Unger |
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| Affiliation: | (1) Faculty of Life Science, Bar-Ilan University, Ramat-Gan, 52900, Israel;(2) The Department of Physics of Complex Systems, The Weizmann Institute of Science, Rehovot, 76100, Israel |
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| Abstract: | Background Detection of non coding RNA (ncRNA) molecules is a major bioinformatics challenge. This challenge is particularly difficult when attempting to detect H/ACA molecules which are involved in converting uridine to pseudouridine on rRNA in trypanosomes, because these organisms have unique H/ACA molecules (termed H/ACA-like) that lack several of the features that characterize H/ACA molecules in most other organisms. |
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