Optical imaging of cell membrane potential changes induced by applied electric fields. |
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Authors: | D Gross L M Loew W W Webb |
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Abstract: | We report the first imaging of the spatial distributions of transmembrane potential changes induced in nonexcitable cells by applied external electric fields. These changes are indicated by the fluorescence intensity of a charge-shift potentiometric dye incorporated in the cell plasma membrane and measured by digital intensified video microscopy. |
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