New anti-MRSA cephalosporins with a basic aminopyridine at the C-7 position |
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| Authors: | Cho A Glinka T W Ludwikow M Fan A T Wang M Hecker S J |
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| Affiliation: | Microcide Pharmaceuticals, Inc., Mountain View, CA 94043, USA. acho@microcide.com |
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| Abstract: | Incorporation of a basic aminopyridine into the C-7 position of 3-(amine-substituted arylthio)-3-norcephalosporins, as in 3, afforded high potency against MRSA and acceptable solubility for intravenous administration. |
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