Activation of endogeneous retroviruses in mouse cells by thermal neutrons |
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| Authors: | O Niwa T Saigusa T Ikushima T Sugahara |
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| Institution: | Department of Pathology, Hiroshima University, Japan. |
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| Abstract: | The effect of thermal neutrons on the induction of murine endogenous viruses from a mouse fibroblast cell line was investigated. Thermal neutrons were more effective than X-rays in induction of endogenous virus as well as in killing of the cells. However, when measured as a function of cell killing, both radiations had similar efficiency of induction. The RBEs of thermal neutrons alone were calculated on the assumption that the contribution of contaminating gamma-rays was additive. It was 4.2 for the killing effect and 4-5 for virus induction. |
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