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Stereospecific synthesis of trans-arachidonic acids.
Authors:U M Krishna  M M Reddy  J Xia  J R Falck  M Balazy
Affiliation:Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Abstract:An effective synthesis is described for the preparation of all four mono trans isomers of arachidonic acid via deoxidation of epoxide precursors with lithium diphenylphosphide and quaternization with methyl iodide.
Keywords:
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