Stem cells deployed for bone repair hijacked by T cells |
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Authors: | Shi Yufang Wei Lixin Wang Ying Ren Guangwen |
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Affiliation: | Key Laboratory of Stem Cell Biology, Institute of Health Sciences, Shanghai Institutes for Biological Sciences of Chinese Academy of Sciences/Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China. yufangshi@sibs.ac.cn |
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Abstract: | Mesenchymal stem cells (MSCs) are a promising source for bone regeneration. Recently, in Nature Medicine, Liu et al. (2011) reported that host lymphocytes secrete IFN-γ and TNF-α to initiate apoptosis of transplanted MSCs and that aspirin can alleviate these effects to improve bone repair. |
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