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Localization of outer surface proteins A and B in both the outer membrane and intracellular compartments of Borrelia burgdorferi.
Authors:J S Brusca   A W McDowall   M V Norgard     J D Radolf
Affiliation:Department of Microbiology, Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas 75235.
Abstract:Borrelia burgdorferi B31 with and without outer membranes contained nearly identical amounts of outer surface proteins A and B. The majority of each immunogen also was localized intracellularly by immunocryoultramicrotomy. These results are inconsistent with the widely held belief that outer surface proteins A and B are exclusively outer membrane proteins.
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