| 环状RNA在不同类型上皮间质转化中的作用 |
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| 引用本文： | 刘艳萍,谭滇湘,张朝晖. 环状RNA在不同类型上皮间质转化中的作用[J]. 生命的化学, 2020, 40(4): 574-578 |
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| 作者姓名： | 刘艳萍 谭滇湘 张朝晖 |
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| 作者单位： | 南华大学公共卫生学院,衡阳421001;衡阳市中心医院麻醉科,衡阳421001 |
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| 摘 要： | 近年来发现环状RNA(circular RNA,circRNA)在各种类型的上皮间质转化(epithelial-mesenchymal transition,EMT)中发挥了重要的作用。本文就EMT的概念和分类、circRNA的分类和生成,以及cir-cRNA分别在EMT过程中作用的国内外研究进展作一综述,以期为发生EMT的器官纤维化、肿瘤等疾病的靶向治疗和预防寻找新的研究方向。
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| 关 键 词： | 环状RNA 上皮间质转化 纤维化 肿瘤 |
Research progress in the roles of circRNA in the different types of epithelial-mesenchymal transition |
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| LIU Yanping,TAN Dianxiang,ZHANG Zhaohui. Research progress in the roles of circRNA in the different types of epithelial-mesenchymal transition[J]. Chemistry of Life, 2020, 40(4): 574-578 |
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| Authors: | LIU Yanping TAN Dianxiang ZHANG Zhaohui |
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| Affiliation: | (School of Public Health,University of South China,Hengyang 421001,China;Department of Anesthesiology,Hengyang Central Hospital,Hengyang 421001,China) |
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| Abstract: | In recent years, circular RNA(circRNA) has been found to play a vital role in various types of epithelial-mesenchymal transition(EMT). To provide evidence for new direction of the treatment and prevention of organ fibrosis and tumors in EMT, we have reviewed the research progress about the concept and three types of EMT, the classification and generation of circRNA, and the role of circRNA in the progress of type Ⅰ, Ⅱ and Ⅲ EMT. |
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| Keywords: | circRNA epithelial-mesenchymal transition fibrosis tumor |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
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