Soy isoflavone aglycone modulates expression of cell surface antigens in vitro and in vivo |
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| Authors: | Harada Toshie Arii Masayuki Tsuji Ryohei F Adachi Yoshiyuki Nakajima Mitsuhiro Yadomae Toshiro Ohno Naohito |
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| Affiliation: | Laboratory for Immunopharmacology of Microbial Products, School of Pharmacy, Tokyo University of Pharmacy & Life Science, Hachioji, Tokyo, Japan. |
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| Abstract: | Soy isoflavone aglycones (IFAs) have a wide range of biological actions. We investigated in this study the effect of IFAs on myeloid cells. The cell surface expression of both CD80 and CD86 was up-regulated by treating myeloid cells with IFAs in vitro and in vivo. The findings suggest that IFAs could modulate the myeloid cell function. |
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