Directional positive selection on an allele of arbitrary dominance |
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Authors: | Teshima Kosuke M Przeworski Molly |
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Affiliation: | Department of Human Genetics, University of Chicago, Chicago, Illinois 60637, USA. kteshima@uchicago.edu |
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Abstract: | Most models of positive directional selection assume codominance of the beneficial allele. We examine the importance of this assumption by implementing a coalescent model of positive directional selection with arbitrary dominance. We find that, for a given mean fixation time, a beneficial allele has a much weaker effect on diversity at linked neutral sites when the allele is recessive. |
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