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Cytophotometric study of blood neutrophil and wound exudate myeloperoxidase in experimental wound healing
Authors:L A Mamedov  A V Nikolaev  V V Zakharov  A B Shekhter  Iu R Khrust
Abstract:Changes in the activity of blood neutrophil and wound exudate myeloperoxidase (MP) have been studied cytophotometrically on the models of aseptic and infected experimental wounds in 220 male Wistar rats on the 1st-10th, 12th and 15th day after wounding. It has been established that changes in MP activity reflect the nature and stages of the pathological process and the animals' reaction to it. MP activity is significantly higher in animals with infected wounds, which indicates the intensity and duration of the inflammatory process and is of prognostic value.
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