| 胶原蛋白肽对高脂日粮小鼠抗氧化能力和血脂代谢的影响 |
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| 引用本文： | 李亚欣,施用晖,王洁昀,林云鉴,乐国伟. 胶原蛋白肽对高脂日粮小鼠抗氧化能力和血脂代谢的影响[J]. 天然产物研究与开发, 2011, 23(1): 54-58,68 |
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| 作者姓名： | 李亚欣 施用晖 王洁昀 林云鉴 乐国伟 |
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| 作者单位： | 1. 江南大学食品学院,无锡,214122
2. 江南大学食,品科学与技术国家重点实验室;江南大学食品学院,无锡,214122 |
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| 基金项目： | 十一五"863项目"，国家科技支撑计划课题 |
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| 摘 要： | 本文探讨胶原蛋白肽对高脂日粮小鼠抗氧化能力及血脂代谢的影响。40只小鼠随机分为5组(n=8):分别饲喂正常日粮,高脂日粮,添加0.5%和1%胶原蛋白肽及0.1%硫辛酸的高脂日粮。42 d后测定小鼠全血(血清)和组织活性氧(Reactive oxygen species,ROS)水平、丙二醛(Malondialdehyde,MDA)含量、抗氧化酶活力及血脂水平。结果表明:0.5%和1%胶原蛋白肽都可显著降低机体ROS水平及MDA含量(P<0.05),增强抗氧化能力(P<0.05),改善血脂水平(P<0.05)。1%胶原蛋白肽能使机体抗氧化能力及血脂水平恢复到正常水平,0.5%的添加量效果不显著。适量的胶原蛋白肽可有效提高机体抗氧化能力,缓解高脂膳食造成的氧化应激,改善血脂代谢。
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| 关 键 词： | 胶原蛋白肽 硫辛酸 高脂日粮 氧化应激 抗氧化能力 血脂代谢 |
Effects of Collagen Peptides on Antioxidant Capacity and Serum Lipid Metabolism of Mice Fed with High-fat Diet |
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| LI Ya-xin,SHI Yong-hui,WANG Jie-yun,LIN Yun-jian,LE Guo-wei. Effects of Collagen Peptides on Antioxidant Capacity and Serum Lipid Metabolism of Mice Fed with High-fat Diet[J]. Natural Product Research and Development, 2011, 23(1): 54-58,68 |
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| Authors: | LI Ya-xin SHI Yong-hui WANG Jie-yun LIN Yun-jian LE Guo-wei |
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| Affiliation: | LI Ya-xin2,SHI Yong-hui1,2,WANG Jie-yun2,LIN Yun-jian2,LE Guo-wei1,21State Key Laboratory of Food Science and Technology,Jiangnan University,2School of Food Science and Technology,Wuxi 214122,China |
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| Abstract: | The effects of collagen peptides on antioxidant capacity and serum lipid metabolism of mice fed with high-fat diet were studied in the present work.Forty mice were randomly divided into 5 groups.They were fed with ordinary diet,high-fat diet,and high-fat diet with 0.5% collagen peptides,1% collagen peptides,and 0.1% lipoic acid,respectively.The level of reactive oxygen species(ROS),contents of malondialdehyde(MDA) and antioxidant enzymes activities in blood(serum) and tissues and serum lipid level were dete... |
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| Keywords: | collagen peptides(CP) lipoic acid(LA) high-fat diet oxidative stress antioxidant capacity serum lipid metabolism |
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