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A method for obtaining large numbers of trophozoites of avirulent strains of Toxoplasma gondii using an antibody to interferon-gamma
Authors:Y Suzuki  J S Remington
Affiliation:Department of Immunology and Infectious Diseases, Palo Alto Medical Foundation, California 94301.
Abstract:Injection of cysts of avirulent strains of T. gondii intraperitoneally into mice that were pretreated with monoclonal antibody against interferon-gamma (IFN-gamma) provided more than 10(7) trophozoites of those strains. This method is suitable for obtaining large numbers of trophozoites of T. gondii strains that are avirulent for mice.
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