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Cardiolipin synthesis during the cell cycle of the yeastSaccharomyces cerevisiae
Authors:M Greksák  K Nejedlý  J Zborowski
Institution:(1) Institute of Experimental Veterinary Medicine, 900 28 Ivanka pri Dunaji;(2) Department of Biochemistry, Faculty of Sciences, J. E. Purkyně University, 611 37 Brno;(3) Department of Cellular Biochemistry, Nencki Institute of Experimental Biology, Warszawa, Poland
Abstract:Cardiolipin synthesis was studied during the aerobio synchronous growth of aerobically grown yeastSaccharomyces cerevisiae. The time course of the synthesis was stepwise and the rise in cardiolipin level in cells coincided in time with the increase in cytochrome oxidase activity. This finding supports the notion of discontinuous completion of the inner mitochondrial membrane and hints at a close relation between cardiolipin and cytochrome oxidase activity.
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