Effects of Anaesthetics on the Mobility of <Emphasis Type="Italic">Dictyostelium discoideum</Emphasis>

REVERSIBLE depolymerization of labile microtubular protein can occur in the presence of anaesthetics at concentrations comparable to those in clinical use¹. Allison and Nunn² proposed a possible mechanism of anaesthesia involving the interaction of inhalational anaesthetics with protein molecules, of which the effect on microtubules is an example.