Amniotomy and Oral Prostaglandin E2 Titration for Induction of Labour

The efficacy of oral prostaglandin E₂ used on a titration basis in association with amniotomy for the induction of labour was investigated in a series of 50 patients. Induction was successful in 29 out of 32 primigravid and 17 out of 18 multigravid patients. The mean induction-delivery intervals in successful cases were 10½ and 6 hours respectively. There were no significant effects on the fetuses.