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Electron dense plaques (calcium binding sites) in the plasma membrane of the endocrine cells in rodent pancreatic islets and parathyroid glands
Authors:Prof Dr Lennart Boquist MD
Institution:(1) Department of Pathology, University of Umeå, Umeå, Sweden;(2) Dept. of Pathology, University of Umeå, S-901 87 Umeå, Sweden
Abstract:Summary Small electron dense plaques (EDP) were found in the plasma membrane of pancreatic islet A-, B- and D-cells and parathyroid chief cells of mice and gerbils. The identification of the EDP was facilitated by the use of special fixation techniques. The EDP may represent sites of calcium binding in the cell membranes.Supported by grants from the Swedish Medical Research Council (Project No. B76-12X-00718-11B)
Keywords:Electron dense plaques  Pancreatic islets  Parathyroids  Electron microscopy  Calcium binding
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