Aflatoxin congener biosynthesis induced by lipoperoxidation |
| |
| Institution: | 1. Dipartimento di Biologia Vegetale, Università di Roma “La Sapienza”, Largo Cristina di Svezia 24, 00165 Rome, Italy;2. Istituto San Gallicano, Via San Gallicano 25/a, 00153 Rome, Italy;1. School of Agriculture and Biology, Shanghai Jiao Tong University, 800 Dongchuan Road, Minhang District, Shanghai, 200240, China;2. Laboratory of Quality and Safety Risk Assessment for Dairy Products of Ministry of Agriculture and Rural Affairs, Institute of Animal Science, Chinese Academy of Agriculture Sciences, Beijing, 100193, China;1. School of Traditional Chinese Medicine, Capital Medical University, Beijing 100069, China;2. Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China;3. State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, 999078, Macau |
| |
| Abstract: | Lipoperoxidation plays a key role in inducing the production of aflatoxins and their congeners (norsolorinic acid, averufin, averantin, versicolorin A, sterigmatocystin, and O-methyl sterigmatocystin) by different strains of Aspergillus parasiticus and Aspergillus flavus. The stimulating effect was obtained by adding epoxides, hydroperoxides, and carbon tetrachloride to culture media. The presence in the media of a free radical scavenger (cysteamine) was capable of inhibiting the output of aflatoxins and their precursors induced by epoxides, hydroperoxides, and carbon tetrachloride. The stimulating effect of lipoperoxidation would appear to take place before the biosynthesis of norsolorinic acid. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
