Inflammatory and Immunological parameters in adults with Down syndrome |
| |
Authors: | Maria BF Trotta João B Serro Azul Mauricio Wajngarten Simone G Fonseca Anna C Goldberg Jorge E Kalil |
| |
Institution: | 1.Heart Institute University of S?o Paulo Medical School,S?o Paulo,Brazil;2.Albert Einstein Hospital,S?o Paulo,Brazil |
| |
Abstract: | Background The increase in life expectancy within the general population has resulted in an increasing number of elderly adults, including
patients with Down syndrome (DS), with a current life expectancy of about 50 years. We evaluate the parameters of humoral
and cellular immune response, the quantitative expression of the regulator of calcineurin1 gene (RCAN1) and the production
of cytokines. The study group consisted of adults DS (n = 24) and a control group with intellectual disability without Down
syndrome (ID) (n = 21) and living in a similar environmental background. It was evaluated serology, immunophenotyping, the
quantitative gene expression of RCAN1 and the production of cytokines. |
| |
Keywords: | |
本文献已被 PubMed SpringerLink 等数据库收录! |
|