Mannosyltransferase activities in membranes from various yeast strains |
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| Authors: | Verostek, Mary Frances Trimble, Robert B. |
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| Affiliation: | 1Wadsworth Center, New York State Department of Health Albany, NY 12201, USA
2Department of Biomedical Sciences, SUNY School of Public Health Albany, NY 12201, USA |
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| Abstract: | In the yeast Golgi compartments, at least five, and potentiallyseveral additional mannosyltransferases are involved in elongatingto mannan the core Man8GlcNAc2 oligosac-charidetrimmed from GlC3Man9GlcNAc2 in the endoplasmic reticulum. Structuralstudies on oligosaccharides from alg3 mutant yeast, which lackthe four upper arm mannoses donated by Man-P-Dol (where Dolis dolichol), verified that the new |
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