Increased sister chromatid exchanges in workers exposed to occupational lead and Zinc |
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Authors: | Hamiyet Dönmez Nurcan Dursun Yusuf özkul Haulil Demirta? |
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Institution: | (1) Department of Medical Biology and Genetics, Erciyes University, Medical Faculty, 38039 Kayseri, Turkey;(2) Department of Physiology, Erciyes University, Medical Faculty, 38039 Kayseri, Turkey |
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Abstract: | Sister chromatid exchange (SCE) in blood lymphocytes was determined in 32 male workers occupationally exposed to lead (Pb)
and zinc (Zn) and in 20 controls matched for age and smoking habits. Exposed workers have higher SCE mean values than control
workers (p < 0.01). In exposed persons, blood Pb concentrations were also significantly higher than controls (p < 0.0001), but the difference between Zn levels in the blood of these groups was not found to be significant (p > 0.05). Our results indicate that Pb may be genotoxic and harmful to human health. |
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Keywords: | Lead zinc sister chromatid exchange |
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