Low-dose zinc administration as an effective Wilson's disease treatment |
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Authors: | Najda J Stella-Hołowiecka B Machalski M |
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Affiliation: | (1) Clinical Department of Internal Diseases and Oncological Chemotherapy, Silesian Medical Academy, ul. Reymonta 8 40-029, Katowice, Poland |
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Abstract: | A case of a 11-yr-long Wilson’s disease treatment in a 16-yr-old boy with neurologic presentation was analyzed and monitored. In the face of severe symptoms of chelator intolerance, a comparatively low dose of 100 mg of zinc has been administered for the entire 11-yr-long treatment. Considerable improvement of clinical status was achieved, with accompanying regression of central nervous system lesion. The parameters of copper metabolism were normalized with effective urine elimination. The low-dose oral zinc intake proved to be therapeutically effective, eliminating further copper tissue toxicity. |
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Keywords: | Wilson’ s disease zinc copper |
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