Monoclonal antibodies to mammalian neurofilaments |
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Authors: | John N Wood Brian H Anderton |
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Institution: | (1) Immunology Department, St. George's Hospital Medical School, Cranmer Terrace, SW17 ORE London, UK |
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Abstract: | Hybrid cell lines secreting monoclonal antibodies against mammalian neurofilaments have been prepared. An improved protocol for the preparation of neurofilaments and methods for the identification and isolation of such hybridomas are presented. The antibodies produced specifically stain only neuronal cell types in both cerebellar sections and culture. |
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