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FOXO protects against age‐progressive axonal degeneration
Authors:Evan Santo  Do‐Yeon Kim  John W Chen  Roderick T Bronson  Jason W Locasale  Yoonmi Na  Jaclyn Lee  Stewart Reed  Miklos Toth  Wai H Yu  Florian L Muller  Jihye Paik
Institution:1. Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA;2. Department of Pharmacology, School of Dentistry, Kyungpook National University, Daegu, Korea;3. Center for Systems Biology and the Division of Neuroradiology, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA;4. Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA, USA;5. Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC, USA;6. Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA, USA;7. Department of Pharmacology, Weill Cornell Medicine, New York, NY, USA;8. Department of Pathology and Cell Biology, Columbia University, New York, NY, USA;9. Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
Abstract:
Keywords:accelerated aging  aging  central nervous system     FOXO     mouse models  neurodegeneration  neuroinflammation  oxidative stress
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