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ENZO: a web tool for derivation and evaluation of kinetic models of enzyme catalyzed reactions
Authors:Bevc Sta?  Konc Janez  Stojan Jure  Hodo??ek Milan  Penca Matej  Praprotnik Matej  Jane?i? Du?anka
Institution:National Institute of Chemistry, Ljubljana, Slovenia.
Abstract:We describe a web tool ENZO (Enzyme Kinetics), a graphical interface for building kinetic models of enzyme catalyzed reactions. ENZO automatically generates the corresponding differential equations from a stipulated enzyme reaction scheme. These differential equations are processed by a numerical solver and a regression algorithm which fits the coefficients of differential equations to experimentally observed time course curves. ENZO allows rapid evaluation of rival reaction schemes and can be used for routine tests in enzyme kinetics. It is freely available as a web tool, at http://enzo.cmm.ki.si.
Keywords:
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