Aspidospermatan–aspidospermatan and eburnane-sarpagine bisindole alkaloids from Leuconotis |
| |
| Authors: | Chew-Yan Gan Yun-Yee Low Ward T Robinson Kanki Komiyama Toh-Seok Kam |
| |
| Institution: | 1. Department of Chemistry, University of Malaya, 50603 Kuala Lumpur, Malaysia;2. Center for Basic Research, Kitasato University, 5-9-1, Shirokane, Minato-ku, Tokyo 108-8642, Japan |
| |
| Abstract: | Leucofoline and leuconoline, representing the first members of the aspidospermatan–aspidospermatan and eburnane-sarpagine subclasses of the bisindole alkaloids, respectively, were isolated from the Malayan Leuconotis griffithii. The structures of these bisindole alkaloids were established using NMR and MS analysis, and in the case of leuconoline, confirmed by X-ray diffraction analysis. Both alkaloids showed weak cytotoxicity towards human KB cells. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
