Adjuvant activity of alum in inducing antigen specific IgE antibodies in BALB/c mice: a reevaluation |
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Authors: | Yamanishi Rintaro Yusa Ikuko Bando Noriko Terao Junji |
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Institution: | Department of Nutrition, School of Medicine, University of Tokushima, Kuramoto-cho 3-18-15, Tokushima-shi, Tokushima 770-8503, Japan. rintaro@nutr.med.tokushima-u.ac.jp |
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Abstract: | The IgE production was compared in the presence and absence of aluminum hydroxide gel (alum). Without alum, the IgE production was induced within a suitable range of the antigen dosage; however, alum enhanced it. Alum did not affect the minimum requirement for the antigen dosage, indicating that alum may not take part in the efficiency of antigen presentation. |
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