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Adjuvant activity of alum in inducing antigen specific IgE antibodies in BALB/c mice: a reevaluation
Authors:Yamanishi Rintaro  Yusa Ikuko  Bando Noriko  Terao Junji
Institution:Department of Nutrition, School of Medicine, University of Tokushima, Kuramoto-cho 3-18-15, Tokushima-shi, Tokushima 770-8503, Japan. rintaro@nutr.med.tokushima-u.ac.jp
Abstract:The IgE production was compared in the presence and absence of aluminum hydroxide gel (alum). Without alum, the IgE production was induced within a suitable range of the antigen dosage; however, alum enhanced it. Alum did not affect the minimum requirement for the antigen dosage, indicating that alum may not take part in the efficiency of antigen presentation.
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