Evaluation of multicomponent recombinant vaccines against Actinobacillus pleuropneumoniae in mice |
| |
| Authors: | Meili Shao Yong Wang Chunlai Wang Yang Guo Yonggang Peng Jiandong Liu Guangxing Li Huifang Liu Siguo Liu |
| |
| Affiliation: | (1) Division of Bacterial Diseases, National Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, 150001 Harbin, China;(2) Northeast Agricultural University, 150030 Harbin, China;(3) Shenyang Agricultural University, 110161 Shenyang, China |
| |
| Abstract: | Background Porcine contagious pleuropneumonia (PCP) is a highly contagious disease that is caused by Actinobacillus pleuropneumoniae (APP) and characterized by severe fibrinous necrotizing hemorrhagic pleuropneumonia, which is a severe threat to the swine industry. In addition to APP RTX-toxins I (ApxI), APP RTX-toxin II (ApxII), APP RTX-toxin III (ApxIII) and Outer membrane protein (OMP), there may be other useful antigens that can contribute to protection. In the development of an efficacious vaccine against APP, the immunogenicities of multicomponent recombinant subunit vaccines were evaluated. |
| |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ |
|
