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Microbial transformation of baccatin VI and 1beta-hydroxy baccatin I by Aspergillus niger |
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| Authors: | Shen Ya-Ching Lo Kuang-Liang Lin Chun-Ling Chakraborty Rupak |
| Affiliation: | Institute of Marine Resources, National Sun Yat-sen University, 70 Lien Hai Road, Kaohsiung 80424, Taiwan, ROC |
| Abstract: | The biotransformation of baccatin VI (1) and 1β-hydroxybaccatin I (2) with the filamentous fungus Aspergillus niger produced four new taxane diterpenoids taxumairol S1 (3), taxumairol T1 (4) and taxumairol S (5), taxumairol T (6), respectively. 1β-Dehydroxybaccatin VI (7) remained unreacted under the same condition. |
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