Prediction of the course of continuous fermentation on the basis of analysis of the batch process

A way of predicting the conditions of product formation in a two-state continuous cultivation on the basis of analyzing the batch process is described. The prediction applies to processes where the product formation is proportional to the growth rate and where the relationship between culture activity and the external conditions is linear. Using the example of glucose oxidase production byAspergillus niger the prediction is borne out. The difference between the predicted and found values does not exceed 15%. Dedicated to Academician Ivan Málek on the occasion of his 60th birthday