A second allele of eppA in Borrelia burgdorferi strain B31 is located on the previously undetected circular plasmid cp9-2 |
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Authors: | Miller J C Bono J L Babb K El-Hage N Casjens S Stevenson B |
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Institution: | Department of Microbiology and Immunology, University of Kentucky College of Medicine, Lexington, Kentucky 40536-0298, USA. |
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Abstract: | Although sequence analysis of Borrelia burgdorferi isolate B31 was recently declared "complete," we found that cultures of this strain can contain a novel 9-kb circular plasmid, cp9-2. The newly described plasmid contains both sequence similarities with and differences from the previously identified B31 plasmid cp9-1 (formerly cp9). cp9-1 and cp9-2 each encode a unique allele of EppA, a putative membrane protein synthesized by B. burgdorferi during mammalian infection. |
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