对萘磺酸钠修饰的石墨烯基纳米银复合抗菌材料的制备及性能评价

制备采用1-萘磺酸钠修饰的石墨烯基纳米银复合材料,并对其性能进行评价。首先制备了石墨烯基纳米银复合材料,采用1-萘磺酸钠修饰,记为AgNP/rGO-NA,然后通过与聚乙烯吡咯烷酮做保护剂的纳米银（PVP/AgNP）的比较,分析其稳定性,抗菌活性,细胞毒性。研究发现,纳米银AgNP在制备的复合材料表面的分布相对均匀,AgNP的质量分数为4.3%,粒径为5~15nm,Zeta电位为-42.5 mV;在无光或光照强度为3000 Lx（勒克斯）的低温光照仪环境下储存10 d,PVP/AgNP聚集作用较为明显,而AgNP/rGO-NA则分散性良好,聚集作用不明显;AgNP/rGO-NA具有更加良好的抗菌活性,生物相容性和相对较低的生物毒性。试验表明经过1-萘磺酸钠修饰的石墨烯基纳米银复合材料质量可靠,性能良好,具有广阔的应用前景。

Preparation and properties of sodium naphthalene sulfonate reduced grapheme oxide-silver nanoparticles composite antibacterial materials

Sodium naphthalene sulfonate（ NA）/reduction grapheme oxide-Silver nanoparticles（ AgNP /rGO-NA） composite materials were prepared to evaluate their quality performance. Sodium naphthalene sulfonate reduced grapheme oxide-silver nanoparticles shortened as AgNP/rGO-NA were prepared and then their stability,antibacterial activity and cellular toxicity were analyzed by comparing with the nanoparticles modified by polyvinylpyrrolidone silver（ PVP/AgNP）. The study found AgNP relatively uniform distribution in AgNP/rGO-NA surface,silver nanoparticles mass fraction is 4. 3%,a particle size is 515 nm,zeta potential of42. 3 mV; under dark or light intensity 3000LX low illumination meter environment（ lux） for 10 days,PVP/AgNP aggregation was more obvious,and the AgNP/rGO-NA good dispersibility,aggregation is not obvious; AgNP/rGO-NA had a more excellent antibacterial activity,biological compatibility and relatively low biological toxicity. AgNP/rGO-NA composite materials has reliable quality,good performance,and has broad application prospects.