Enhanced affinity of ketotifen toward tamarind seed polysaccharide in comparison with hydroxyethylcellulose and hyaluronic acid: a nuclear magnetic resonance investigation |
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| Authors: | Uccello-Barretta Gloria Nazzi Samuele Balzano Federica Di Colo Giacomo Zambito Ylenia Zaino Chiara Sansò Marco Salvadori Eleonora Benvenuti Marco |
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| Affiliation: | Università di Pisa, Dipartimento di Chimica e Chimica Industriale, Via Risorgimento 35, I-56126 Pisa, Italy. gub@dcci.unipi.it |
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| Abstract: | Nuclear magnetic resonance (NMR) spectroscopy demonstrated that, in aqueous solution, ketotifen fumarate bound more strongly to tamarind seed polysaccharide (TSP) than to hydroxyethylcellulose or hyaluronic acid. Results were confirmed by dynamic dialysis technique. |
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