Stem cells and skin regeneration |
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Authors: | Staniszewska Marzena Słuczanowska-Głąbowska Sylwia Drukała Justyna |
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Institution: | Department of Physiology, Pomeranian Medical University, Szczecin, Poland. stanma@sci.pam.szczecin.pl |
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Abstract: | Stem cells represent a great hope for regenerative medicine. In adult life, stem cell deposits are kept in organ niches; the need for tissue or organ regeneration mobilizes stem cells via the SDF-1-CXCR4 regulation axis. Constant regeneration of the skin is achieved due to stem cell differentiation within the epidermis and the hair follicle; thus, skin may serve as an excellent source of stem cells. This is of paramount importance in the treatment of chronic skin wounds and burns. |
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