Frequency of micronucleated cells in the mouse bone marrow after exposure to various doses of gamma-radiation

The frequency of micronucleated cells was determined in the bone marrow of female BALB/c mice exposed to different doses of gamma-radiation at 1, 3, 10 and 14 days post irradiation. The frequency of micronucleated cells increased with the increase in exposure dose at all time period studied. However, the frequency of micronucleated cells declined with time irrespective of exposure dose. The dose-response curve thus obtained was linear.