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Antigenic structure of the foot-and-mouth virus. V. Protection of naturally susceptible animals from foot-and-mouth disease using a synthetic peptide |
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| Authors: | A V Iarov V M Gel'fanov L A Grechaninova A Iu Surovo? O M Vol'pina V T Ivanov A V Chepurkin N N Driagalin V M Ivaniushchenkov |
| Abstract: | We have synthesized the peptide representing 135-159 VP1 sequence of A22 strain of the foot-and-mouth disease virus (FMDV). The synthetic peptide induced 100% protection of guinea pigs against the disease. Two-fold immunization of cuttle with the peptide and single immunization of sheep induced full protection of the animals against A22 strain of FMDV. |
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